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Paper 8

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Blastocystis hominis and colorectal cancer

Author Howard W. Steer
Institution Southampton General Hospital,
Southampton University Hospitals NHS Trust,
University of Southampton School of Medicine,
Southampton, SO16 6YD United Kingdom.
Copyright © Howard Steer 2007.

All rights reserved. This publication is copyright under the Berne Convention and the International Copyright Convention. No part of this publication may be reproduced, stored in a retrieval system or transmitted, in any form or by any means without the prior permission of the copyright holder. Enquires concerning reproduction outside the scope of the above should be sent to: mail@howardsteer.co.uk.

Abstract

The protozoan parasite, blastocystis hominis, has been studied by transmission electron microscopy in the stool samples of 320 patients. Various ultrastructural characteristics are noted and the incidence of this parasite infestation studied. The vacuolar form is the most common form. There is a strong correlation between the disease condition and the presence of blastocystis hominis (p<0.0001).The commonest infection was seen in patients having pruritis ani (54.2%) or carcinoma of the colon/rectum confined to the bowel wall or regional lymph nodes (53%) compared with patients having other intestinal diseases (30%). The implications of this finding with respect to colorectal cancer and the aetiology of this condition are discussed.



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